Twentyone Hotel Rome, Rome - Reviews, Room Options & Prices 2025

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Key details

About the Hotel

Via Cola Di Rienzo 23, Rome, Italy, 00192

Twentyone Hotel, a 4-star boutique property in the elegant Prati district, sits halfway between the Vatican Museums and Spanish Steps, offering panoramic views of St Peter's Dome and the Vittoriano.

Designer Room Amenities

Twentyone Hotel features 93 rooms with custom-made designer furniture, LCD TVs with satellite channels, free WiFi, and private terraces on the fifth floor Deluxe rooms. Junior suites include Jacuzzis and round beds.

Italian Dining Experience

Bistrò 21 serves traditional Roman and Italian cuisine with rotating daily specialties: gnocchi on Mondays, fish on Tuesdays and Fridays, meat on Thursdays, and soup on Wednesdays.

Villa Borghese Access

Hotel Twenty One provides direct access to Villa Borghese's Italian gardens and vast open spaces, ideal for walking, running, and picnics.

Central Transit Location

Located 0.2 miles from Lepanto metro station, the hotel is 2 miles from Roma Termini and a 15-minute walk to Vatican City and Saint Peter's Basilica.

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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals

Twin Room

Max:

2 persons

18 m²

Bed options:

2 Single beds

Shower

Heating

room details

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Triple Room

Max:

3 persons

22 m²

Bed options:

3 Single beds

Shower

Heating

room details

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Queen Room

Max:

2 persons

18 m²

Bed options:

1 King Size Bed

Shower

Heating

room details

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Price and Room Availability Calendar

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Getting around

A guide to all available transportation options

City Center

Rome 1.4 mi

Airports

Ciampino (CIA) 11.6 mi

Fiumicino (FCO) 18.4 mi

Train

Roma San Pietro Train Station 1.2 mi

Metro stations

Lepanto Metro Station1400 ft

Facilities

Experience a variety of amenities at the boutique hotel, crafted to ensure your comfort and unforgettable moments

Wi-Fi

Parking

EUR 35 per day

Baggage storage

24-hour services

24-hour reception

General

Non-smoking rooms
Wi-Fi
Parking
Safe deposit box
24-hour reception
Express check-in/ -out
No pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Security
Baggage storage
Allergy-free rooms
Elevator
Barber shop
Coffee shop
Smoke detectors
Electric vehicle charging station
Fire extinguishers
Key card access

Sports & Fitness

Fitness center

Services

Paid airport shuttle
Room service
Housekeeping
Laundry
Dry cleaning
Tours/Ticket assistance
Welcome drink

Dining

In-room breakfast
Restaurant
Snack bar
Bar/ Lounge area
Packed lunches
Special diet menus

Business

Fax/Photocopying

Children

Cribs
Children's buffet

Facilities for people with disabilities

Toilet for disabled
Bathroom for disabled

Spa & Leisure

Garden area
Leisure/ TV room

Room features

Air conditioning
Heating
Mini-bar
Soundproofed rooms
Sitting area
Terrace
Garden furniture
Tea and coffee facilities
Ironing facilities

Bathroom

Free toiletries
Sink

Media

Flat-screen TV
AM/FM alarm clock

Room decor

Carpeted floor

Location

Via Cola Di Rienzo 23, Rome, Italy, 00192

Map view

street view

Via Cola Di Rienzo 23, Rome, Italy, 00192

City landmarks

Fountains

Trevi Fountain

1.1 mi

Church

Pantheon

5200 ft

Square

The Colosseum

1.8 mi

Landmark

Piazza Navona

4400 ft

Museums

Vatican Museums

1.0 mi

Church

St. Peter's Basilica

1.1 mi

Square

Saint Peter's Square

4900 ft

Largo della Salara Vecchia

Roman Forum

1.5 mi

Piazza di Spagna

4500 ft

Square

Spanish Steps

5000 ft

Bridges

St. Angelo Bridge

3500 ft

Square

Piazza del Popolo

2500 ft

Square

Piazza Venezia

1.3 mi

Church

Sistine Chapel

1.1 mi

Cemetery

Altar of the Fatherland

1.4 mi

Square

Campo de' Fiori

1.1 mi

Piazza San Pietro

Vatican City

1.1 mi

Museums

Borghese Gallery and Museum

1.2 mi

Bridges

St. Angelo Bridge

3600 ft

Vatikanstadt 00120 Città del Vaticano VA

Torre di San Giovanni

1.6 mi

Church

Church of Saint Louis the French

4500 ft

Square

Largo di Torre Argentina

1.1 mi

Church

Church of Santa Maria del Popolo

2300 ft

Zoo

Bioparco di Roma

1.3 mi

Church

Santa Maria in Trastevere

1.4 mi

Museums

Capitoline Museums

1.3 mi

Square

Piazza Barberini

1.1 mi

Museums

Museum of the Ara Pacis

3000 ft

Square

Pincian Hill

3200 ft

Church

Church of the Gesu

1.2 mi

Nearby

Bridges

St. Angelo Bridge

3500 ft

Square

Piazza del Popolo

2500 ft

Bridges

St. Angelo Bridge

3600 ft

Church

Church of Santa Maria del Popolo

2300 ft

Church

Basilica of Sant' Agostino

3400 ft

Restaurants

Bistro' 21

100 ft

Via Cola di Rienzo 23 Hotel Twenty One

Cantieri Bistrot

300 ft

Via Cola di Rienzo 16

Le Sicilianedde

300 ft

Via Cola di Rienzo

La Pinseria Prati

300 ft

Via Lucrezio Caro 60

Pasticceria Sanzini

500 ft

Via Valadier

Ristorante Grekos Taste the Myth

700 ft

Via Dei Gracchi 282 Incrocio via Marcantonio Colonna

Ruyi

800 ft

Via Valadier 14

Quelli del bar Cicerone

600 ft

Via Cicerone 68

Reviews and Ratings

Feedback from previous guests about their experience.

68%

enjoyed the hotel and would happily stay again

6.8/10

Nice

Rooms

7.8

Location

9.0

Service

7.5

Dining

7.0

4/5 based on 1904 reviews

#365 of 1,380 hotels in Rome based on Tripadvisor

Mary

United Kingdom, March 2025

6.4/10

I had a pleasant stay at Hotel Twentyone, with its comfortable and modern room and helpful staff. The location made it easy to explore Rome, being within walking distance to many attractions like the Vatican. However, the breakfast service left something to be desired, with some staff not being as accommodating as I hoped.

Rooms

8.0

My room was on the fifth floor, upgraded to a junior suite with a lovely double aspect balcony. The space felt large and modern, which was fantastic since I prefer that over dated decor. Though I did notice some minor issues with the bathroom's layout, it didn’t detract much from my experience.

Service

7.0

The reception team was incredibly friendly and went out of their way to assist with everything I needed. However, I did encounter some challenges with the breakfast staff who were less responsive when I asked for certain items.

Location

9.0

The hotel is situated in a lively area with plenty of cafes and shops nearby. It's also conveniently located just a 15-minute walk from the Vatican and a very short stroll across the bridge to Piazza del Popolo.

Dining

6.0

Breakfast was served buffet style in a charming ground floor café, offering a variety of pastries and hot options. However, it often felt like some items were missing, and staff appeared overwhelmed when I needed assistance.

Facilities

8.0

The hotel had solid facilities, including secured parking which is a real gem in Rome. I also appreciated the efficient checkout and luggage storage service.

Samuel

United Kingdom, March 2025

6.2/10

I had a great experience at Twentyone Hotel in Rome. The location was fantastic, close to the Vatican and many local shops and restaurants (I found some amazing gelato nearby!). However, the wifi was a bit slow, and there were no English channels on TV.

Rooms

9.0

My room was spacious and clean, featuring air conditioning that worked perfectly during the warm October weather. I especially loved the balcony view of St. Peter's Basilica.

Service

8.0

The staff was exceptionally friendly and helpful, always ready to provide recommendations or assistance. However, I was disappointed that my pre-arrival request for a surprise for my wife was not addressed.

Location

10.0

The hotel's location is ideal for exploring Rome. It was only a short walk to major attractions like the Vatican and even the Colosseum (I appreciated being in a quieter neighborhood).

Dining

7.0

The breakfast was decent, offering a buffet-style selection, though nothing amazing. The rooftop dining option was a highlight, providing lovely views.

Facilities

8.0

The hotel had good facilities, including a reliable mini-bar and the convenience of room amenities. However, I wished there were more toiletries provided in the bathroom.

William

United Kingdom, November 2024

7.4/10

My stay at Twentyone Hotel had its positives, particularly its fantastic location close to major attractions like the Vatican and plenty of local eateries. However, I faced several challenges during my visit, especially with the room temperature and noise levels. The staff was accommodating, but the overall experience did not meet my expectations.

Rooms

6.0

The room I stayed in was of decent size, but the decor in dark shades made it feel a bit gloomy. I appreciated the deep tub in the bathroom, yet the ambiance was noticeably dark and sometimes uninviting. Despite the issues, the cleanliness was commendable.

Service

5.0

While the staff was friendly and I received prompt service for requests, my complaints about the room conditions felt overlooked. I had issues with the air conditioning, and despite seeking assistance, the response was less than satisfactory.

Location

8.0

The hotel's location was a standout feature, with easy access to local shops and restaurants, and it was just a walk away from the Vatican and other key sights. This was a definite highlight of my stay.

Dining

7.0

Breakfast options were varied and fresh, but I found room service to be overpriced. It might have been more enjoyable to eat at one of the many nearby cafes instead.

Facilities

6.0

Facilitating various amenities was convenient, and the presence of a parking garage was a plus. However, the limitations in room appliances, such as the absence of a kettle initially, were disappointing.

Luna

United Kingdom, October 2024

7.2/10

My stay at Twentyone Hotel was filled with both highlights and a few drawbacks. The location was perfect for exploring Rome's major attractions, and the staff were incredibly helpful in providing recommendations and assistance (which made my experience even better!). However, I did find the rooms to be on the small side, and the bed was quite firm, making it a bit tricky for a good night's sleep.

Rooms

8.0

I found the room to be clean and well-equipped, but it was smaller than I expected and lacked sufficient storage for my belongings (which can be a bit of a pain). The contemporary decor was nice, and I appreciated having a mini-bar for my drinks.

Service

10.0

The reception staff were exceptionally friendly and welcoming (I felt genuinely cared for). They provided me with a map and explained the best ways to navigate the public transport options around the city, which I found invaluable.

Location

9.0

The hotel’s location just minutes away from the metro and key tourist sites was fantastic (I could easily walk to places like the Vatican and the Colosseum!). It was nice being in a quieter neighborhood while still being close to everything.

Dining

8.0

Breakfast was decent, offering a good variety of options, though nothing particularly special (but it definitely filled me up for my daily excursions!). The rooftop restaurant provided beautiful views, especially during the evening.

Facilities

8.0

Facilities were well-maintained, and I was pleased with the available amenities like the efficient WiFi in the restaurant (which was a plus, as I had some work to tackle). I also liked the option of using their room service.